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Drug overdose in children.

J Tibballs, E J McArdle, T C Brown

    Australian Paediatric Journal
    |February 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Accidental drug poisoning in young children remains common, while self-poisoning rises in adolescents. Two deaths resulted from suicide attempts, with some cases involving children under 10.

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    Area of Science:

    • Pediatric Toxicology
    • Epidemiology of Poisoning
    • Child Health

    Background:

    • Review of 478 pediatric drug poisoning admissions over five years (1978-1982).
    • Analysis of epidemiological factors, drug types, management, and outcomes.
    • Focus on trends in accidental versus intentional ingestions.

    Observation:

    • Accidental ingestion prevalent in younger children; self-poisoning increasing in ages 8-17.
    • Suicide attempts and self-destructive ingestions comprised 11.5% of cases, including two fatalities.
    • Iatrogenic poisoning occurred in 11% of cases, often involving metoclopramide or prochlorperazine.

    Findings:

    • Benzodiazepines, major tranquilizers, and antihistamines were the most frequently ingested drug classes.
    • Tricyclic antidepressant poisoning led to the highest number of Intensive Care Unit admissions.

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  • Management principles for pediatric drug poisoning were discussed.

    • Implications:

    • Highlights the evolving patterns of pediatric drug poisoning, emphasizing both accidental and intentional exposures.
    • Underscores the need for targeted prevention strategies for different age groups.
    • Informs clinical management protocols for healthcare providers dealing with pediatric poisonings.