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Updated: Jun 3, 2025

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
Published on: December 21, 2019
Treatment of Pleural Mesothelioma: ASCO Guideline Update
Hedy L Kindler1, Nofisat Ismaila2, Lyudmila Bazhenova3
1University of Chicago Medicine, Chicago, IL.
Purpose:
To provide evidence-based recommendations to practicing physicians and others on the management of pleural mesothelioma (PM).
Methods:
ASCO convened an Expert Panel of medical oncology, thoracic surgery, radiation oncology, pathology, cancer genetics, and advocacy experts to conduct an updated literature search, which included systematic reviews, meta-analyses, randomized controlled trials, and prospective and retrospective comparative observational studies published from 2016 through 2024. Outcomes of interest included survival, disease-free or recurrence-free survival, and quality of life. Expert Panel members used available evidence and informal consensus to develop evidence-based guideline recommendations.
Results:
The literature search identified 110 additional relevant studies to inform the evidence base for this guideline.
Recommendations:
Evidence-based recommendations were developed for surgical cytoreduction, immunotherapy, chemotherapy, pathology, and germline testing in patients with PM.Additional information is available at www.asco.org/thoracic-cancer-guidelines.
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