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Updated: Jun 3, 2025

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
Published on: February 2, 2024
Lyme disease periprosthetic joint infection
Theodore Yang1, Fnu Shweta2, Marcus Greatens3
1Medical College of Wisconsin - Central Wisconsin Campus, Wausau, Wisconsin, USA.
Abstract:
Periprosthetic joint infection (PJI) is a devastating complication of total joint surgery. Surgical management of PJI has increased surgical risks and is costly to the healthcare system. This case study presents a unique clinical scenario involving a patient who was diagnosed with Lyme PJI at the total knee arthroplasty site after undergoing surgical management. Lyme PJI is a rare condition, and there is limited guidance on the diagnosis and management of this condition. It should be considered in the differential of certain individuals with appropriate epidemiological risk factors. This report aims to highlight the complexities associated with the diagnosis and management of periprosthetic Lyme infections.
Insights
Periprosthetic joint infection (PJI) is a serious complication of joint replacement surgery. This case study highlights the rare diagnosis and complex management of Lyme PJI in a total knee arthroplasty patient.
Area of Science:
- Orthopedic Surgery
- Infectious Diseases
- Rheumatology
Background:
- Periprosthetic joint infection (PJI) poses significant challenges following total joint arthroplasty.
- Current management strategies for PJI involve complex surgical interventions with associated risks and costs.
- Lyme disease is an emerging cause of PJI, yet it remains underdiagnosed and poorly understood.

