Related Experiment Video
Updated: Jun 3, 2025
07:07
A High-throughput Method for Measurement of Glomerular Filtration Rate in Conscious Mice
Published on: May 10, 2013
43.3K
Comment on: "Measured glomerular filtration rate based on iohexol: Towards an application in liver transplantation."
Paul Carrier1, Jean-Baptiste Woillard2, Marilyne Debette-Gratien1
1Service d'Hépato-gastroentérologie. CHU Dupuytren. 2, avenue Martin Luther Ling. 87042 Limoges. France; Unité Mixte de Recherche UMR-1248 « Pharmacologie et Transplantation », Faculté de Médecine et de Pharmacie, Université de Limoges. 2, rue du Dr Marcland, 87024 Limoges, France.
Abstract
No abstract available in PubMed .
Related Concept Videos
01:23Renal Clearance
711
The glomerular filtration rate (GFR) is a critical marker of kidney function, reflecting the efficiency of filtration by the glomeruli. Renal clearance of specific substances, such as inulin or creatinine, is commonly used to measure GFR.
Renal clearance refers to the volume of plasma cleared of a specific substance, such as creatinine, per unit of time. To measure clearance, urine samples are collected over a 24-hour period during each bladder voiding, followed by a single blood sample at the...
Renal clearance refers to the volume of plasma cleared of a specific substance, such as creatinine, per unit of time. To measure clearance, urine samples are collected over a 24-hour period during each bladder voiding, followed by a single blood sample at the...
711
01:02Renal Drug Excretion: Glomerular Filtration
137
The kidney serves as the primary organ responsible for eliminating drugs and their metabolites from the body. This process, known as renal elimination, starts with glomerular filtration and results in urine formation. Each kidney houses millions of functional units called nephrons, where urine production occurs. A nephron has two main components: a renal corpuscle and a renal tubule.
Drugs gain access to the kidney via the renal artery, which progressively branches off into afferent arterioles....
Drugs gain access to the kidney via the renal artery, which progressively branches off into afferent arterioles....
137