Related Experiment Video
Updated: Jun 8, 2026
10:52
Protocols for Robust Herbicide Resistance Testing in Different Weed Species
Published on: July 2, 2015
14.6K
A Non-Volatile Pro-Dicamba Herbicide Inspired by Meclofenoxate.
Joel Haywood1,2, Karen J Breese1, M Jordi Muria-Gonzalez2
1School of Molecular Sciences, The, University of Western Australia, 35 Stirling Highway, Crawley, Perth, 6009, Australia.
Chemistry (Weinheim an Der Bergstrasse, Germany)
|January 8, 2025
Summary
A new non-volatile dicamba herbicide derivative was developed. This pro-dicamba shows herbicidal activity and is compatible with new crop technologies, offering a safer alternative to traditional dicamba formulations.
Area of Science:
- Agricultural Chemistry
- Plant Science
- Herbicide Development
Background:
- Dicamba is a widely used herbicide known for its volatility and drift issues.
- Meclofenoxate exhibits significant herbicidal properties.
- There is a need for effective, non-volatile herbicides to mitigate environmental risks.
Purpose of the Study:
- To develop a non-volatile derivative of dicamba.
- To assess the herbicidal efficacy and plant uptake of the new derivative.
- To evaluate the compatibility of the pro-dicamba with dicamba monooxygenase tolerance technology.
Main Methods:
- Synthesis of a dicamba derivative by ester-bonding with 2-dimethylaminoethanol.
- Evaluation of the derivative's volatility and herbicidal activity.
- Assessment of in-planta hydrolysis to dicamba and 2-dimethylaminoethanol.
- Testing compatibility with dicamba monooxygenase tolerance systems.
Main Results:
- The synthesized dicamba derivative is non-volatile.
- The derivative retains herbicidal efficacy.
- It enters plants intact and hydrolyzes to active dicamba within leaf tissues.
- Pro-dicamba demonstrates compatibility with dicamba monooxygenase tolerance technology.
Conclusions:
- The developed pro-dicamba is a non-volatile and herbicidally active compound.
- This derivative offers a potentially safer alternative to conventional dicamba, reducing drift concerns.
- Its compatibility with tolerance technologies suggests broad applicability in modern agriculture.
Related Concept Videos
01:27Nondepolarizing (Competitive) Neuromuscular Blockers: Pharmacological Actions
Nondepolarizing neuromuscular blockers prevent the membrane depolarization of muscle cells and inhibit muscle contraction. These are usually administered with anesthetics to achieve complete muscle relaxation. Upon administration, these drugs first block the small, rapidly contracting muscles of the face and hands, followed by the larger muscles of the trunk and the intercostal muscles. The diaphragm is the last muscle to be affected.
Although all competitive neuromuscular blockers are designed...
Although all competitive neuromuscular blockers are designed...
01:11Nondepolarizing (Competitive) Neuromuscular Blockers: Pharmacokinetics
All neuromuscular blocking agents are injected intravenously because they are poorly absorbed from the GI tract. Rapid onset is achieved with intravenous administration, although absorption is also adequate from an intramuscular injection. Since these agents are highly ionized, they do not readily penetrate cell membranes or cross the blood-brain barrier.
Instead, they are transported by the blood to different tissues. Muscles with a greater blood supply (arteries) and blood flow receive more...
Instead, they are transported by the blood to different tissues. Muscles with a greater blood supply (arteries) and blood flow receive more...
01:27Chemical Agents for Microbial Control
Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
01:28Microbial Bioremediation of Pesticides
Pesticides often feature structurally complex chemical architectures, incorporating halogen groups and multiple aromatic rings. These characteristics confer high chemical stability, rendering many pesticides resistant to natural degradation processes. This resistance poses significant environmental concerns, as persistent pesticide residues can accumulate in ecosystems and affect non-target organisms.Despite the inherent stability of many pesticides, certain microorganisms possess the metabolic...
01:18Production of Biopesticides
Biopesticides offer a sustainable alternative to chemical pesticides, utilizing microbial agents to control agricultural pests. Bacillus thuringiensis (Bt) is a widely employed bacterium known for its potent insecticidal activity. Bt biopesticides are favored for their specificity to insect pests, minimal environmental impact, and natural degradability.Mechanism of Bt Toxin Action Bt produces insecticidal crystal (Cry) proteins during its sporulation phase. These proteins form parasporal...
01:15Anthelminthic Agents
Anthelmintic drugs differ significantly from antiparasitic therapies targeting protozoa, primarily due to differences in parasite biology. Whereas most protozoal treatments act on proliferating cells, anthelmintics are typically directed against mature, nonproliferative helminths. The therapeutic approach considers the helminth's reliance on neuromuscular coordination, glucose metabolism, and microtubular integrity for survival, reproduction, and localization within the host. Most anthelmintics...