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Emerging Roles of Dermal Fibroblasts in Hyperpigmentation and Hypopigmentation: A Review

Xingyue Gao1, Wenzhong Xiang2

  • 1Department of Dermatology, Hangzhou Third People's Hospital, Zhejiang Chinese Medical University, Zhejiang, Hangzhou, China.

Journal of Cosmetic Dermatology
|January 9, 2025
PubMed
Summary

Dermal fibroblasts significantly influence skin pigmentation by secreting factors that either promote or inhibit melanin production. Understanding these fibroblast-derived signals offers new therapeutic targets for treating pigmentary disorders like melasma and vitiligo.

Keywords:
cytokinefibroblastsmelanocytespigmentation

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