Distinguishing the Bimodal Interaction of a Squaraine Dye with a Protein by a Functional Group Photodeprotection
Palapuravan Anees1,2, Giridharan Saranya1, Sivaramapanicker Sreejith3
1Chemical Sciences and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Thiruvananthapuram, 695019, India.
Chemistry, an Asian Journal
|January 9, 2025
Abstract:
In this study, we present a protecting group photocleavage method to investigate both covalent and noncovalent interactions between a squaraine dye (PSq) and Bovine Serum Albumin (BSA). This approach allows for the photoinduced activation and deactivation of PSq fluorescence, providing valuable insights into the dual-mode interaction of the dye with the protein.
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