Related Experiment Video
Updated: Jun 3, 2025

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
Published on: September 26, 2019
Diaper dermatitis and associated factors among children aged 0-24 months in low- and middle-income countries: A
Atoma Negera1, Midekso Sento2, Debela Dereje1
1Nursing Department, College of Health Science, Mattu University, Mattu Town, Oromia Regional State, Ethiopia.
Insights
Diaper dermatitis (DD) is a common infant skin condition, affecting up to 70% of young children. This study will determine the overall prevalence of DD and its contributing factors in low- and middle-income countries.
Area of Science:
- Pediatrics
- Dermatology
- Public Health
Background:
- Diaper dermatitis (DD) is a prevalent skin condition affecting the diaper area, particularly in infants aged 9-12 months.
- Approximately 70% of infants and young children experience DD, with up to 25% seeking medical care.
Purpose of the Study:
- To estimate the pooled prevalence of diaper dermatitis (DD).
- To identify factors associated with DD in low- and middle-income countries (LMICs).
Main Methods:
- A systematic literature search will be conducted across multiple electronic databases.
- Studies from LMICs reporting DD prevalence will be included, adhering to PRISMA-P guidelines.
- Meta-analysis using a random-effects model will estimate pooled prevalence and associated factors, with study quality assessed by JBI appraisal checklists.
Main Results:
- The study will provide an estimated pooled prevalence of diaper dermatitis in LMICs.
- Associated factors contributing to diaper dermatitis will be identified.
Conclusions:
- This systematic review and meta-analysis will offer crucial insights into the burden of diaper dermatitis in LMICs.
- Findings will inform public health strategies and clinical management of DD in vulnerable populations.
Background:
Diaper dermatitis (DD, sometimes known as diaper rash or napkin dermatitis is one of the most prevalent skin infections that occur in the area covered by the diaper. Although diaper dermatitis can be seen in any patient wearing diapers, it is reported to be more common in infants aged 9-12 months. Approximately, 70% of infants and young children suffer from diaper dermatitis at some point during their diaper wearing years and up to 25% of children seek healthcare due to this case.
Methods And Analysis: Methods And Analysis:
A comprehensive literature search will be gathered from electronic databases such as PubMed, Embase, Hinari, Cochrane Library, African Journals Online (AJOL), and Google Scholar. The protocol followed the Preferred Reporting Items for Systematic Reviews and Meta-analyses for Protocol (PRISMA-P) guideline. All studies conducted in low- and middle-income countries (LMICs) will be included regardless of their study design as long as these studies report the magnitude of the problem under study. Joanna Briggs Institute's (JBI) appraisal checklist will be used to assess the quality of individual studies. Heterogeneity will be checked using Cochrane Q test statistics and I2 test statistics, and a random-effects model will be employed to estimate the pooled prevalence of DD and its associated factors.
Ethics And Dissemination Of Research:
Ethics committee approval or written informed consent will not be required to conduct this review, and meta-analysis for the review will be entirely based on published data. The result of this study will be submitted to a peer-reviewed journal, and it will also be presented at relevant research conferences.
Results:
The present study will estimate the pooled prevalence of diaper dermatitis and their associated factors in low- and middle-income countries.
Trial Registration:
PROSPERO registration number: CRD42024578550.
More Related Videos
09:36Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers
Published on: July 28, 2022
06:47Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
Published on: September 27, 2017
Related Concept Videos
Anatomy of the Intestines
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
Immunodeficiency Diseases
There are three main causes of immunodeficiency...
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Attention-Deficit/Hyperactivity Disorder
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...