Radical Resection of a Radial Ewing Sarcoma and Ulnar Centralization in a 10-Month-Old Girl: A Case Report

Area of Science:

• Pediatric Oncology
• Orthopedic Surgery
• Limb Reconstruction

Background:

• Ewing sarcoma is a rare bone cancer primarily affecting children and young adults.
• Involvement of the entire radius is exceptionally uncommon, particularly in infants.
• Effective management strategies for such extensive pediatric bone tumors are critical.

Purpose of the Study:

• To present a unique case of a 10-month-old infant with Ewing sarcoma of the entire radius.
• To describe the surgical and oncological management of this rare presentation.
• To evaluate the functional and aesthetic outcomes of a novel limb-sparing surgical approach.

Main Methods:

• A 10-month-old female infant diagnosed with Ewing sarcoma of the entire radius.
• Treatment involved neoadjuvant chemotherapy, achieving a near-complete response.
• A subsequent limb-sparing procedure included radical resection of the radius and centralization of the carpus to the ulna.

Main Results:

• The neoadjuvant chemotherapy was highly effective, leading to a significant tumor response.
• The radical resection and carpus centralization procedure preserved limb function.
• The surgical construct demonstrated stability over two years post-operation.

Conclusions:

• This case represents the first reported instance of Ewing sarcoma involving the entire radius in a 10-month-old infant.
• The described surgical technique of radius resection and carpal centralization offers a viable limb-sparing option.
• Excellent functional and aesthetic outcomes were achieved, with construct stability maintained long-term.