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Updated: Jun 3, 2025

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Predicting Discharge Destination From Inpatient Rehabilitation Using Machine Learning.

Hans E Anderson1, Alexandra O Polovneff2, Matthew J Durand1

  • 1Department of Physical Medicine and Rehabilitation, Medical College of Wisconsin, Milwaukee, Wisconsin.

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Machine learning models can predict inpatient rehabilitation discharge destinations, identifying key factors like length of stay and patient conditions for better care transitions.

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Area of Science:

  • Rehabilitation Medicine
  • Health Informatics
  • Artificial Intelligence in Healthcare

Background:

  • Predicting patient discharge destination from inpatient rehabilitation is crucial for care coordination and efficient healthcare resource use.
  • Previous studies have explored factors influencing discharge disposition, but advanced predictive modeling remains an area for development.

Purpose of the Study:

  • To develop and evaluate machine learning models for predicting discharge disposition (home vs. nonhome) for patients in inpatient rehabilitation.
  • To identify key patient and encounter-specific factors associated with home versus nonhome discharges.

Main Methods:

  • Utilized a dataset of 4922 patient encounters from 4401 patients at a Midwestern academic inpatient rehabilitation facility.
  • Tested fifteen distinct machine learning models, including a bagging classifier with a decision tree base, employing random undersampling.
  • Input variables comprised demographic and hospital encounter-specific data.

Main Results:

  • The best-performing model, a bagging classifier, achieved an area under the receiver operating characteristic curve of 0.722.
  • Shapley value analysis identified length of stay, intravenous medication, urinary dysfunction, age, white blood cell count abnormalities, plasma sodium levels, and fatigue as significant predictors.
  • The dataset included 3687 home discharges and 1235 nonhome discharges.

Conclusions:

  • Machine learning models demonstrate efficacy in predicting inpatient rehabilitation discharge disposition.
  • The study successfully identified critical factors influencing whether patients are discharged to home or nonhome settings.
  • Findings can inform clinical decision-making and resource allocation to optimize patient transitions from rehabilitation.