Optimal CPAP Weaning Approaches: A Scoping Review

Joy Adeku1, Sarah Defore, Desi Newberry

  • 1Author Affiliations: Duke University School of Nursing, Durham (Ms Adeku, Mrs Defore, Dr Newberry, and Ms Yates); University of North Carolina Neonatology, Chapel Hill (Dr Newberry); and Duke University Neonatology, Durham, North Carolina (Ms Yates).

Insights

Weaning premature infants from continuous positive airway pressure (CPAP) requires assessing infant readiness. Evidence-based, stepwise interventions improve outcomes regardless of the specific CPAP weaning method used.

Area of Science:

  • Neonatal Medicine
  • Pediatric Pulmonology
  • Respiratory Care

Background:

  • Bronchopulmonary dysplasia (BPD) is a common chronic lung disease in premature infants, causing lasting respiratory issues and increased healthcare costs.
  • Lung injury is a primary cause of BPD, highlighting the need for strategies to prevent progression from respiratory distress syndrome.

Purpose of the Study:

  • To review methods for weaning preterm infants off continuous positive airway pressure (CPAP).
  • To assess the effectiveness of different CPAP weaning strategies in maintaining respiratory independence.
  • To identify research gaps and guide future studies on optimizing CPAP weaning for preterm infants.

Main Methods:

  • Scoping review of existing literature.
  • Analysis of four randomized controlled trials comparing different CPAP weaning approaches (sudden, gradual, non-sprinting, sprinting).

Main Results:

  • The review discusses four randomized controlled trials on CPAP weaning methods for premature infants.
  • Successful weaning depends on accurately assessing the infant's readiness.

Conclusions:

  • Consistent implementation of evidence-based interventions and a stepwise approach are crucial for improving patient outcomes.
  • The chosen weaning methodology is less critical than the consistent application of best practices and readiness assessment.
Abstract

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