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Updated: Jun 3, 2025

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Published on: February 10, 2023
Barriers and facilitators for improving oral anticoagulant medication adherence in lower extremity deep venous
Xiaoyu Wu1, Huaqin Wang1, Ya Tan1
1The Clinical Nursing Teaching and Research Section of the Second Xiangya Hospital, 410011, Central South University, Changsha, Hunan Province, China.
Background:
Deep venous thrombosis (DVT) of the lower extremity causes a major disease burden globally. Currently, oral anticoagulant therapy is used as the first-line treatment of DVT, however, medication non-adherence remains a serious problem for postoperative spinal surgery patients whose DVT incidence is at a high level.
Aims:
To explore barriers and facilitators affecting patient oral anticoagulant medication adherence, based on guidance using the COM-B model.
Methods:
This study was a qualitative study using a descriptive research design with in-depth and semi-structured interviews. Data were analyzed adopting traditional content analysis methods.
Results:
Based on the COM-B theoretical model, we identified 9 barriers and facilitators from capability, opportunity, and motivation domains.
Conclusions:
Patients were confronted with barriers from capability, opportunity, and motivation domains, which were not isolated but interrelated. Future interventions should incorporate facilitators and barriers to address medication adherence issue with a holistic approach at multiple levels.
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