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Updated: Jun 3, 2025

Manual Restraint and Common Compound Administration Routes in Mice and Rats
Published on: September 26, 2012
Essential resources and best practices for laboratory mouse research
Rosa Haque1, Aysenur Deniz Song2, Jongsun Lee1
1Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, South Korea.
Abstract:
The laboratory mouse (Mus musculus) is the most widely used mammalian model organism in biomedical and life science research. This concise guide aims to provide essential information to assist researchers new to working with mice, covering topics such as mouse husbandry, maintenance, and available resources for obtaining mouse strains and associated data. Additionally, we discuss ethical considerations, emphasizing the 3Rs (replacement, reduction, and refinement) to ensure responsible and humane research practices.

