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Essential resources and best practices for laboratory mouse research.

Rosa Haque1, Aysenur Deniz Song2, Jongsun Lee1

  • 1Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, South Korea.

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This guide offers essential information for researchers new to using laboratory mice (Mus musculus). It covers husbandry, resources, and ethical considerations, including the 3Rs for humane animal research.

Keywords:
Animal researchMouse databaseMouse experiments

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Area of Science:

  • Biomedical Research
  • Life Sciences
  • Animal Models

Background:

  • The laboratory mouse (Mus musculus) is a cornerstone of biomedical and life science research.
  • This guide serves as an essential resource for researchers new to mouse models.

Discussion:

  • Covers critical aspects of mouse husbandry and maintenance.
  • Details available resources for acquiring mouse strains and data.
  • Addresses ethical considerations and the 3Rs (replacement, reduction, refinement) in animal research.

Key Insights:

  • Provides practical information for novice researchers.
  • Ensures responsible and humane research practices are highlighted.
  • Facilitates efficient use of mouse models in scientific studies.

Outlook:

  • Aims to improve the quality and reproducibility of research using mice.
  • Promotes ethical standards in animal experimentation.
  • Supports the advancement of biomedical and life science discoveries.