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Liberalism and mitochondrial replacement technique.

Marco Tang1

  • 1Philosophy, University of Waterloo, Waterloo, Ontario, Canada m27tang@uwaterloo.ca.

Journal of Medical Ethics
|January 9, 2025
PubMed
Summary
This summary is machine-generated.

Liberalism must permit partners with female-assigned physiology (PFP) access to mitochondrial replacement technique (MRT). This ensures equal opportunity for genetically related offspring and upholds reproductive autonomy, challenging restrictive arguments.

Keywords:
Ethics- MedicalGene Transfer TechniquesPaternalismPersonal AutonomyReproductive Medicine

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Area of Science:

  • Bioethics
  • Reproductive Technology
  • Liberal Political Philosophy

Background:

  • Mitochondrial replacement technique (MRT) offers solutions for women with mitochondrial diseases.
  • MRT can enable partners with female-assigned physiology (PFP) to have genetically related children.
  • Existing ethical debates question PFP access to MRT based on autonomy and social narratives.

Purpose of the Study:

  • To strengthen the liberal defense for PFP access to MRT.
  • To argue for MRT accessibility based on equality and autonomy principles.
  • To address criticisms regarding the necessity and social implications of MRT for PFPs.

Main Methods:

  • Philosophical argumentation drawing on liberal political theory.
  • Analysis of existing ethical arguments by Cavaliere, Palacios-Gonzalez, and Baylis.
  • Comparison of MRT with other therapeutic interventions, such as cosmetic surgery.

Main Results:

  • The use of MRT by PFPs is permissible, even if considered therapeutic, aligning with social uses of medical interventions.
  • A desire for genetically related offspring, or self-replication, is a valid interest for accessing MRT.
  • Concerns about harmful social narratives are insufficient grounds to restrict PFP access to MRT.

Conclusions:

  • The liberal state must permit PFPs to use MRT.
  • MRT access for PFPs promotes equal opportunity in experiencing genetically related offspring.
  • Autonomy and equality necessitate allowing PFPs to utilize MRT for reproductive purposes.