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Dabie bandavirus and Mycoplasma pneumoniae co-infection: a case report
Yasi Tu1, Miao Deng1, Xueying Zhang1
1Jiangxi Medical Center for Critical Public Health Events, Department of Infectious Diseases, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, No.17 Yongwai Street, Donghu District, Nanchang, 330006, Jiangxi Province, China.
Background:
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by Dabie bandavirus (DBV). We report a case of DBV and Mycoplasma pneumoniae (MP) co-infection.
Case Presentation:
Here we reported a 57-year-old healthy male who was admitted with the presentations of fever, cough, hemoptysis, and hypotension. Laboratory investigations revealed thrombocytopenia, leukopenia, and organ dysfunction of liver and kidney. Seroconversion from Mycoplasma IgM antibody to IgG was recorded, and SFTS was confirmed through metagenomic next-generation sequencing. In addition, hemophagocytic lymphohistiocytosis was diagnosed in the context of DBV and MP coinfection. The patient exhibited a rapid recovery following treatment with omadacycline and essential symptomatic and supportive treatment.
Conclusions:
We firstly reported a case with DBV and MP coinfection, which reminded us that the symptoms of DBV infection were bewildering and easy to miss diagnosis when it was co-infection with other etiologies.
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