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Related Concept Videos

Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...
Ultrasound II: Endoscopic Ultrasound and FibroScan01:25

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Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
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Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test01:22

Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test

In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess the...
Portal Hypertension01:22

Portal Hypertension

Portal hypertension is an increase in blood pressure within the portal venous system. Normally, this pressure is less than 5 mmHg. It is considered clinically significant when it rises above 10 mmHg. At this threshold, complications from altered blood flow and venous congestion emerge.EtiologyPortal hypertension arises from conditions that impede blood flow through the liver. The most common cause is cirrhosis, in which chronic liver injury leads to fibrotic scarring. This fibrosis narrows or...
Ascites01:19

Ascites

DefinitionAscites is the buildup of fluid inside the peritoneal cavity. It occurs when fluid moves out of the vascular system faster than the peritoneal lymphatics can remove it. This fluid shift is most commonly seen in liver cirrhosis but can also appear in several other systemic disorders.EtiologyCirrhosis remains the leading cause of ascites. Other conditions that can contribute include:Heart failureConstrictive pericarditisAbdominal cancersNephrotic syndromeSevere protein–calorie...

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Infectious imaging with indium-111-labeled nonspecific polyclonal human immunoglobulin.

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Related Experiment Video

Updated: May 20, 2026

Rat Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) Procedure
07:29

Rat Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) Procedure

Published on: August 14, 2017

False-positive liver scan due to ascites.

M G Velchik

    Clinical Nuclear Medicine
    |January 1, 1985
    PubMed
    Summary

    False-positive liver scans can occur due to external structures like breast tissue or lung masses. Loculated ascites presents a unique challenge, often requiring advanced imaging like ultrasound or CT for accurate diagnosis.

    Area of Science:

    • Medical Imaging
    • Diagnostic Radiology
    • Nuclear Medicine

    Background:

    • Liver scans can be affected by extrahepatic structures, leading to false-positive results simulating intrahepatic lesions.
    • Common causes include breast tissue, costal margin, kidney, pleural effusion, and lung masses, which attenuate gamma rays.
    • Standard maneuvers like breast elevation or changing projection can often resolve these artifacts.

    Observation:

    • A case is presented where loculated ascites caused a false-positive liver scan.
    • Conventional maneuvers to correct for extrahepatic attenuation were ineffective in this specific case.
    • The cross-sectional imaging capabilities of ultrasound and CT were crucial for accurate diagnosis.

    Findings:

    • Loculated ascites can mimic intrahepatic pathology on standard liver scans.

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  • Simple artifact-reduction techniques may fail when ascites is the confounding factor.
  • Ultrasound and CT provide superior visualization of ascites, differentiating it from true liver lesions.

    • Implications:

    • Accurate interpretation of liver scans requires awareness of potential artifacts.
    • Complex cases of false-positive liver scans may necessitate advanced imaging modalities.
    • Distinguishing ascites from intrahepatic lesions is critical for appropriate patient management and treatment planning.