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Related Experiment Videos

Palpable spleens in newborn term infants.

F Mimouni, P Merlob, S Ashkenazi

    Clinical Pediatrics
    |April 1, 1985
    PubMed
    Summary

    In newborns, the spleen tip was palpable in 17.9% within 24 hours of birth. Spleen enlargement was typically not pathological, except in cases of ABO hemolytic disease.

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    Area of Science:

    • Neonatal Medicine
    • Pediatric Imaging
    • Clinical Pediatrics

    Background:

    • Assessing spleen size in neonates is crucial for identifying potential health issues.
    • Normal spleen size variations in newborns require clear definition for accurate clinical interpretation.

    Purpose of the Study:

    • To establish the normal range of spleen tip palpability in term infants.
    • To determine the incidence and degree of spleen tip palpation within the first 24 hours of life.

    Main Methods:

    • Physical examination of spleen palpability was performed on 470 appropriate-for-gestational-age, full-term infants.
    • Measurements were taken within the initial 24 hours post-delivery.

    Main Results:

    • The spleen tip was palpable in 17.9% of the infants studied.
    • Palpable spleens extended <1 cm (11.7%), 1-2 cm (3.6%), and ≥2 cm (2.6%) below the costal margin.
    • Only two infants with ABO hemolytic disease showed spleen enlargement.

    Conclusions:

    • Spleen palpability in a small percentage of term neonates is common within 24 hours of birth.
    • Most cases of palpable spleen tip in newborns are not indicative of pathology.
    • ABO hemolytic disease is a potential cause of neonatal splenomegaly.

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