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Updated: Jun 3, 2025

Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts
Published on: June 13, 2019
Localized Synchronous Pulmonary Langerhans Cell Sarcoma and Langerhans Cell Histiocytosis
Sachi Kawagishi1, Tomohiro Maniwa1, Hirokazu Watari1
1Department of General Thoracic Surgery, Osaka International Cancer Institute, Osaka, Japan.
Abstract:
A synchronous presentation of pulmonary lesions of Langerhans cell sarcoma (LCS) and Langerhans cell histiocytosis (LCH) is extremely rare. We report the case of a 57-year-old man with 3 pulmonary nodules, 1 in the left lung and 2 in the right lung. In a 2-stage operation, he first underwent a left segmentectomy, and the nodule was diagnosed as LCS. Thereafter, 1 of the 2 right pulmonary nodules disappeared. The residual nodule was resected by right segmentectomy and was diagnosed as LCH. This is a report of complete resection of localized, synchronous pulmonary lesions of LCS and LCH.
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