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Updated: Jul 13, 2026

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Published on: June 12, 2021
Impella 5.5 Use in the Setting of Severe Aortic Insufficiency: A Relative Contraindication
Omar M Sharaf1, Christopher Bobba1, Matheus P Falasa1
1Department of Surgery, University of Florida Health, Gainesville, Florida.
Abstract:
Moderate or severe aortic insufficiency is a contraindication to transvalvular Impella left ventricular assist device (Abiomed) use out of concern for worsening valvular insufficiency and recirculation. This report describes the case of a 75-year-old man with severe eccentric aortic insufficiency and systemic hypoperfusion who was supported with a transvalvular Impella 5.5 device for 6 days as preoperative rehabilitation before aortic valve replacement. The Impella device provided adequate systemic tissue perfusion, and left ventricular function remained without signs of volume overload and recirculation. Moderate or severe aortic insufficiency may not be an absolute contraindication to transvalvular Impella use, although this is case dependent.
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