Related Experiment Video
Updated: Jun 3, 2025

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion
Published on: November 10, 2023
Salvage Pleurectomy/Decortication After Immunotherapy for Sarcomatoid Malignant Pleural Mesothelioma
Kenta Kajiyama1, Akihiro Taira1, Masaru Takenaka1
1Second Department of Surgery (Chest Surgery), University of Occupational and Environmental Health, Japan, Kitakyushu, Japan.
Abstract:
Sarcomatoid malignant pleural mesothelioma (MPM) is a highly aggressive malignant tumor. Surgery may not be recommended, and chemotherapy is less effective. More recently, immunotherapy has become a new standard treatment of care for advanced MPM across all histologic subtypes. This reports describes a case of salvage lung-sparing surgery (pleurectomy with decortication) after immunotherapy with nivolumab in combination with ipilimumab for sarcomatoid MPM. The surgical specimen showed that a major pathologic response was achieved with immunotherapy. The present case indicates not only the feasibility of pleurectomy with decortication after immunotherapy but also pathologic evidence of the efficacy of immunotherapy, which provides insight into the treatment of advanced MPM.
More Related Videos
07:54Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
Published on: December 21, 2019
04:04Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
Related Concept Videos
Pneumothorax-II
Clinical Manifestations:
Endoscopic Studies I: Bronchoscopy and Thoracoscopy
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due...
Flail Chest-II
Assessment:
1. Clinical Evaluation:
History:
Pleural Disorders: Types and Brief Description
Pleura of the Lungs
Pleural Effusion II: Symptoms and Management
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations: