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Increasing Bone Regeneration in Maxillary Sinus Augmentation Using Platelet-rich Fibrin: An Interventional Pre-Post
Xuan Thuy Nguyen1, Lam Nguyen Le2, Thao Thi Do3
1Faculty of Odonto-Stomatology, Nam Can Tho University, Can Tho City, Vietnam.
The Journal of Contemporary Dental Practice
|January 10, 2025
Summary
Platelet-rich fibrin (PRF) effectively augmented bone levels in maxillary sinus augmentation (MSA) for immediate implant placement. This method promoted healing and increased bone thickness without bone grafting, showing high implant stability.
Area of Science:
- Dentistry
- Regenerative Medicine
- Oral Surgery
Background:
- Maxillary sinus augmentation (MSA) is crucial for dental implant placement in atrophic maxillae.
- Traditional methods often involve bone grafting, which can increase morbidity.
- Platelet-rich fibrin (PRF) is a bioactive material that promotes tissue healing and regeneration.
Purpose of the Study:
- To evaluate the efficacy of using only platelet-rich fibrin (PRF) in maxillary sinus augmentation (MSA).
- To assess the impact of PRF on guided bone regeneration during immediate implant placement.
- To determine the clinical outcomes of PRF-alone MSA for immediate implant-supported rehabilitation.
Main Methods:
- An interventional before-after study involved 30 patients undergoing immediate implant placement with PRF-alone MSA.
- Cone-beam computed tomography (CBCT) was used for pre- and post-operative assessments.
- Implant stability was measured using the implant stability quotient (ISQ) device.
Main Results:
- PRF-alone MSA demonstrated significant bone augmentation, increasing bone width and height.
- High initial implant stability (ISQ > 70) was achieved, particularly in D2 bone density.
- No significant post-operative pain, inflammation, or bone loss was observed at 6 months, though complications occurred in 16.7% of cases.
Conclusions:
- Exclusively using PRF is highly effective for bone augmentation in MSA procedures.
- PRF facilitates guided bone regeneration and enhances bone thickness for immediate implant placement.
- This technique offers a promising alternative for immediate implant-supported rehabilitation in the maxilla.
