Related Experiment Video

Updated: Jun 3, 2025

Author Spotlight: Exploring the Role of Inflammation in the Co-occurrence of Primary Sjogren's Syndrome and Lung Adenocarcinoma
10:21

Author Spotlight: Exploring the Role of Inflammation in the Co-occurrence of Primary Sjogren's Syndrome and Lung Adenocarcinoma

Published on: September 20, 2024

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Interplay of Transcriptomic Regulation, Microbiota, and Signaling Pathways in Lung and Gut Inflammation-Induced

Beatriz Andrea Otálora-Otálora1, César Payán-Gómez2, Juan Javier López-Rivera3

  • 1Grupo de Investigación INPAC, Unidad de Investigación, Fundación Universitaria Sanitas, Bogotá 110131, Colombia.

Cells
|January 10, 2025
PubMed
Summary

Inflammation influences cancer development by altering gene networks and signaling pathways in pulmonary arterial hypertension, Crohn's disease, and ulcerative colitis. This study identifies key regulatory RNAs and pathways involved in cell adaptation to inflammation, potentially driving cancer hallmarks.

Keywords:
inflammation-induced tumorigenesis modelsinflammatory-related cell membrane receptorslong non-coding RNAsmicrobiotaoral–gut–lung axissignaling pathwaystranscription factorstranscriptional regulatory network

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