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Updated: Jun 3, 2025

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A Protocol for Analyzing Hepatitis C Virus Replication
Published on: June 26, 2014
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Medicaid Policy and Hepatitis C Treatment Among Rural People Who Use Drugs
Thomas J Stopka1, Bridget M Whitney2, David de Gijsel3
1Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA.
Medical Care
|January 10, 2025
Summary
Restrictive Medicaid policies for hepatitis C virus (HCV) treatment in rural areas are linked to lower treatment rates and cure among people who use drugs (PWUD). Lifting these restrictions is crucial for HCV elimination.
Area of Science:
- Public Health
- Infectious Diseases
- Health Policy
Background:
- Restrictive Medicaid policies for hepatitis C virus (HCV) treatment may worsen rural health disparities for people who use drugs (PWUD).
- This study assessed the association between state-level Medicaid treatment restrictions and HCV treatment initiation and cure among rural PWUD.
Purpose of the Study:
- To evaluate how Medicaid policies restricting HCV treatment impact treatment rates and cure among rural PWUD.
- To determine if specific policy restrictions (prescriber type, sobriety, fibrosis) influence HCV treatment outcomes.
Main Methods:
- Cross-sectional, ecological analysis of state-specific Medicaid policies in 8 rural US sites across 10 states.
- Merged policy data with participant survey data from 944 PWUD; used bivariate and logistic regression analyses to assess associations between restrictions and HCV treatment outcomes.
Main Results:
- 111 (12%) participants received HCV treatment; those treated were older, more likely to receive disability support, and less likely to be Medicaid-insured.
- PWUD in states without restrictions had higher rates of treatment initiation (17% vs. 11%) and HCV cure (42% vs. 30%) compared to those in states with restrictions.
- Medicaid restrictions were associated with lower odds of HCV treatment receipt (OR=0.61) and cure (OR=0.60).
Conclusions:
- Significant associations exist between Medicaid restrictions and lower HCV treatment and cure rates among rural PWUD.
- Removing remaining state-level Medicaid restrictions is essential for achieving hepatitis C virus elimination goals.
- Addressing policy barriers is critical to reducing health disparities in HCV care for vulnerable populations.
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