Related Experiment Video
Updated: Jun 3, 2025
Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
Prognostic implications of regional lung impairment evaluation in quantitative computed tomography imaging of
D Molena Seraphim1, R A Camargo Guassu1, M Alvarez1
1São Paulo State University, Institute of Biosciences, Botucatu, Brazil.
Aim:
To enhance the understanding of COVID-19 regional lung damage pattern by analyzing the organ in subregions, beyond the typical lobe segmentation.
Materials And Methods:
This study used semiautomatic computed tomography (CT) imaging segmentation and quantification to investigate regional lung impairments in patients with COVID-19. Each lung was divided into 12 regions, and the anatomical impairments obtained from the CT image (emphysema, ground glass opacity, and collapsed tissue) were quantified. Then, the results for every region were correlated with clinical outcomes. This research encompassed 333 individuals, both COVID positive (n = 190) and COVID negative (n = 143), whose medical reports were checked for the need for ventilatory support and outcome (cure or deceased).
Results:
Findings indicate a strong association between the extent of lung damage and COVID-19 diagnosis, the level of ventilatory assistance required, and patient survival rates. Notably, the medial posterior lung region exhibited increased opacities and collapse in COVID-positive patients (p < 0.05), particularly those requiring invasive ventilation or who succumbed to the illness.
Conclusion:
The results expand the knowledge of COVID-19 regional impact beyond typical lobe segmentation and indicate that COVID-19 impairments in the lungs are localized. The most affected region identified was the medial posterior of both right and left lungs. Early detection of quantifiable lung damage can serve as a valuable prognostic tool, helping to pinpoint patients at heightened risk of severe complications or mortality.
Related Concept Videos
01:30Radiological Investigation II: MRI and Ventilation Perfusion Scan
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
01:27Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
01:20Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...