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Updated: Aug 10, 2026

Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging
Published on: December 30, 2016
Multicompartment kinetic model for lead. III. Lead in blood plasma and erythrocytes
Abstract:
Multicompartment models have been fitted to experimental data on plasma lead and blood lead concentrations of subjects studied by P. E. deSilva (Brit. J. Ind. Med. 38, 209-217, 1981) and one subject studied by W.I. Manton and C.R. Malloy (Brit. J. Ind. Med. 40, 51-57, 1983). Nonlinear models for plasma lead vs blood lead in populations provide significantly better descriptions than does a linear model. Short-term kinetic data do not clearly resolve the precise nonlinear mechanism, however, Parameters of plasma and erythrocyte distribution in a single subject were significantly different on two occasions.
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