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Organ Preservation After Immune Checkpoint Inhibition for Locally Advanced Rectal Cancer

Charlotte Claeys1, Antoon Billiet1, Karin Haustermans2

  • 1Department of Gastroenterology/Digestive oncology, University Hospital Leuven, Leuven, Belgium.

Clinical Colorectal Cancer
|January 10, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Immune checkpoint inhibitionLocally advanced rectal cancerMSI-HNeoadjuvant therapyTotal neoadjuvant treatment

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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