Association between five novel anthropometric indices and erectile dysfunction in US adults from NHANES database

Area of Science:

• Urology
• Metabolic Syndrome
• Public Health

Background:

• Erectile dysfunction (ED) is a significant global health concern affecting millions of men.
• The relationship between novel anthropometric indices and ED requires further investigation.

Purpose of the Study:

• To examine the association between five novel anthropometric indicators—lipid accumulation products index (LAP), triglyceride glucose index (TyG), waist triglyceride index (WTI), weight-adjusted-waist index (WWI), and a body shape index (ABSI)—and the prevalence of ED.

Main Methods:

• Utilized cross-sectional data from the National Health and Nutrition Examination Survey (NHANES) from 2001 to 2004.
• Included 1413 adult men aged 20-85 years.
• Employed logistic regression, smooth curve fitting, subgroup analyses, and generalized additive models, adjusting for confounding factors.

Main Results:

• After adjusting for confounders, ED showed a positive correlation with LAP (OR=1.0031, P<0.05), TyG (OR=1.2981, P<0.05), WTI (OR=1.4220, P<0.05), WWI (OR=1.6043, P<0.001), and ABSI (OR=1.6211, P<0.05).
• Smooth curve fitting and subgroup analyses confirmed the stability of these associations.
• The study identified a significant positive correlation between the five novel anthropometric indicators and ED prevalence.

Conclusions:

• This study demonstrates a significant positive association between LAP, TyG, WTI, WWI, and ABSI and the prevalence of ED in adult men.
• These novel anthropometric indicators may serve as potential markers for assessing ED risk.
• Further research is warranted to elucidate the underlying mechanisms connecting these indices to ED.