Adsorption of tear proteins on soft contact lenses

To better understand protein deposit formation on contact lenses, a study of adsorption of lacrymal proteins was undertaken. Purified tear proteins were radiolabelled with 125I. The time course of adsorption of single protein solutions at various pHs or in mixture systems at pH 7.5 was determined. The maximum amount of lysozyme and albumin adsorbed in the presence of diluted tears was obtained. The influence of an early adsorbed layer on further adsorption was investigated.