Related Experiment Video
Updated: May 13, 2026

Primary Culture of Human Vestibular Schwannomas
Published on: July 20, 2014
Brain with coexistent acoustic schwannoma and ependymoma
Haofuzi Zhang1, Peng Zou2, Wei Lin1
1Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Background:
This particular case is a world-first with no previous literature reports on patients presenting with both benign acoustic schwannoma and malignant ependymoma.
Case Presentation:
A 60-year-old woman with unexplained right-sided hearing loss that had worsened progressively over 4 years, along with intermittent dizziness that had begun 3 years prior. Our preliminary diagnosis included: (1) Right acoustic neuroma; (2) Ependymoma of the fourth ventricle; and (3) Hydrocephalus. We employed the right sigmoid sinus posterior approach combined with the posterior median approach, beginning with removal of the fourth ventricle tumor and then proceeding to acoustic schwannomas resection through rotating operation positions.
Conclusions:
The case presented significant challenges owing to: The difficulty encountered in arriving at a diagnosis; The difficulty in choosing a suitable surgical approach; The complexity of the surgical sequence; The intricacy of the surgical process. It's rare, complex, and had excellent surgical results.
Related Concept Videos
Cranial and Spinal Meninges
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Brain Abscess l: Introduction
Cerebral Edema ll: Pathophysiology

