Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Microbial Biosensors

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Adaptive graph learning of microbial phylogeny enables accurate and interpretable microbiome-based host phenotype prediction.

Applied and environmental microbiology·2026

Same author

Cognitive Versus Software-based Fusion Targeted Biopsy for the Diagnosis of Clinically Significant Prostate Cancer: A Multicenter, Randomized, Noninferiority Trial (IMAGINATION).

European urology·2026

Same author

Telerobotic partial nephrectomy and radical prostatectomy using a hybrid network: A single-center prospective experience.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2026

Same author

Clinical Outcomes of Orchiopexy and the Risk of Malignancy in Postpubertal Cryptorchid Patients.

Andrology·2026

Same author

Size-dependent ruthenium/ceria nanozymes synchronize catalytic ROS scavenging and electrostatic mtDNA sequestration for periodontitis therapy.

Journal of nanobiotechnology·2026

Same author

Linking hydrocarbon gradients to microbial community variation across full-depth water columns in the Western Pacific Ocean.

Marine environmental research·2026

Search research articles

Related Experiment Video

Updated: Jul 1, 2026

Optical Detection of E. coli Bacteria by Mesoporous Silicon Biosensors

Optical Detection of E. coli Bacteria by Mesoporous Silicon Biosensors

Published on: November 20, 2013

SERS-Based Local Field Enhancement in Biosensing Applications.

Yangdong Xie¹, Jiling Xu¹, Danyang Shao¹

¹State Key Laboratory on Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun 130012, China.

Molecules (Basel, Switzerland)

|January 11, 2025

Summary

Surface-enhanced Raman scattering (SERS) offers sensitive molecular identification. Recent advancements focus on novel SERS substrates like colloidal, chip-based, and tip-enhanced systems for broader applications.

Keywords:

SERS biological detection composite nanoparticles plasma

More Related Videos

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Published on: February 16, 2018

Exploring Biomolecular Interaction Between the Molecular Chaperone Hsp90 and Its Client Protein Kinase Cdc37 using Field-Effect Biosensing Technology

Exploring Biomolecular Interaction Between the Molecular Chaperone Hsp90 and Its Client Protein Kinase Cdc37 using Field-Effect Biosensing Technology

Published on: March 31, 2022

Related Experiment Videos

Last Updated: Jul 1, 2026

Optical Detection of E. coli Bacteria by Mesoporous Silicon Biosensors

Optical Detection of E. coli Bacteria by Mesoporous Silicon Biosensors

Published on: November 20, 2013

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Ultrasensitive Detection of Biomarkers by Using a Molecular Imprinting Based Capacitive Biosensor

Published on: February 16, 2018

Exploring Biomolecular Interaction Between the Molecular Chaperone Hsp90 and Its Client Protein Kinase Cdc37 using Field-Effect Biosensing Technology

Exploring Biomolecular Interaction Between the Molecular Chaperone Hsp90 and Its Client Protein Kinase Cdc37 using Field-Effect Biosensing Technology

Published on: March 31, 2022

Area of Science:

Materials Science
Spectroscopy
Nanotechnology

Background:

Surface-enhanced Raman scattering (SERS) is a powerful technique for molecular identification.
Its applications span biological detection, environmental monitoring, and food safety.
SERS substrate materials have evolved significantly, moving beyond precious metals to diverse nanostructures.

Purpose of the Study:

To review the latest advancements in SERS substrates.
To explore colloidal, chip-based, and tip-enhanced Raman spectroscopy systems.
To provide insights into future trends and challenges in SERS substrate development.

Main Methods:

Review of recent literature on SERS substrate materials.
Analysis of design principles and functionalities of emerging SERS substrates.
Discussion of factors influencing SERS signal enhancement in nanomaterials.

Main Results:

Significant evolution in SERS substrate materials from precious metals to semiconductors and complex nanostructures.
Detailed examination of colloidal, chip-based, and tip-enhanced Raman spectroscopy.
Identification of key factors driving SERS signal enhancement.

Conclusions:

Future SERS substrate development requires focus on efficiency and cost-effectiveness.
Multifunctional SERS substrates are crucial for real-world applications.
Continued innovation in nanomaterials will drive SERS technology forward.