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Maximal Intensity Exercise Induces Adipokine Secretion and Disrupts Prooxidant-Antioxidant Balance in Young Men with
Magdalena Wiecek1, Mateusz Mardyla1, Jadwiga Szymura2
1Department of Physiology and Biochemistry, Institute of Biomedical Sciences, Faculty of Physical Education and Sport, University of Physical Education in Kraków, 31-571 Kraków, Poland.
Maximal exercise impacts energy balance and causes oxidative stress. Body composition does not significantly alter these effects, though high fat mass may affect antioxidant enzyme activity.
Area of Science:
- Exercise physiology
- Biochemistry
- Sports science
Background:
- Maximal physical exertion disrupts energy homeostasis and induces oxidative stress.
- Adipokines play a role in regulating metabolism and may be influenced by exercise.
- Understanding the interplay between exercise, body composition, and metabolic markers is crucial for athletes and health professionals.
Purpose of the Study:
- To investigate the impact of maximal intensity exercise on prooxidant-antioxidant balance and adipokine secretion.
- To determine if these exercise-induced changes are dependent on body composition in young, healthy individuals.
- To assess specific oxidative stress markers and key adipokines before and after maximal exercise.
Main Methods:
- Blood samples were collected from young men with varying body compositions (average, high muscle, high fat mass) before and after maximal exercise.
- Concentrations of advanced protein oxidation products (AOPP), DNA/RNA oxidation, lipid peroxidation (LPO), antioxidant enzymes (CAT, SOD, GPx), and adipokines (visfatin, leptin, resistin, adiponectin, asprosin, irisin) were measured.
- Post-exercise results were corrected for plasma volume changes.
Main Results:
- Maximal exercise increased lipid peroxidation (LPO) and resistin in all groups.
- Individuals with higher fat mass showed increased catalase (CAT) and decreased superoxide dismutase (SOD) activity.
- Maximal exercise affected six of twelve parameters (LPO, CAT, SOD, visfatin, resistin, asprosin), with body composition having an insignificant effect overall.
Conclusions:
- Maximal intensity exercise induces resistin secretion and lipid damage irrespective of body composition.
- Higher fat mass may predispose individuals to exercise-induced disruptions in antioxidant enzyme activity.
- Plasma volume changes must be considered when evaluating post-exercise biochemical markers.
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