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Hypnosis Sedation Used in Breast Oncologic Surgery Significantly Decreases Perioperative Inflammatory Reaction
Martine Berliere1, Fabienne Roelants2, François P Duhoux1
1Breast Clinic, King Albert II Cancer Institute, Clniques Universitaires Saint Luc, Université Catholique de Louvain, 1200 Woluwé-Saint-Lambert, Belgium.
Hypnosis sedation significantly reduced postoperative pain and anxiety in breast cancer surgery patients. This approach also lowered inflammatory markers, suggesting a beneficial role in perioperative recovery.
Area of Science:
- Oncology
- Anesthesiology
- Psychosomatic Medicine
Background:
- Hypnosis sedation is emerging as an alternative anesthesia method for breast oncologic surgery.
- Assessing its impact on patient recovery and inflammatory response is crucial.
Purpose of the Study:
- To evaluate the efficacy of hypnosis sedation compared to general anesthesia in breast cancer surgery.
- To analyze its effects on pain, anxiety, distress, and inflammatory markers.
Main Methods:
- A prospective, non-randomized study included 284 patients undergoing breast surgery.
- Patients were divided into three groups: general anesthesia (GA), GA with hypnorelaxation (GAVRH), and exclusive hypnosis sedation (HYPS).
- Pain, anxiety, distress, neutrophil-to-lymphocyte ratio (NLR), and C-reactive protein (CRP) were measured.
Main Results:
- Hypnosis sedation (HYPS) group showed statistically lower pain and anxiety scores on postoperative days 1 and 8.
- Patients in the HYPS group had reduced non-steroidal anti-inflammatory drug (NSAID) consumption.
- NLR and CRP levels were significantly lower on postoperative day 1 for patients receiving hypnosis sedation.
Conclusions:
- Hypnosis sedation offers benefits in reducing postoperative pain and NSAID use in breast cancer surgery.
- These clinical benefits are associated with a significant reduction in perioperative inflammatory markers.
- Hypnosis sedation presents a promising approach for enhancing recovery in oncologic surgery.
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