Related Experiment Video
Updated: Jun 3, 2025
06:29
Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
10.2K
CAR/CSACI Practice Guidance for Contrast Media Hypersensitivity.
Adam Byrne1,2, D Blair Macdonald3,4, Iain D C Kirkpatrick5,6
1Department of Pediatrics, Division of Infectious Disease, Immunology & Allergy, University of Ottawa, Ottawa, ON, Canada.
Summary
Pretreatment with diphenhydramine and corticosteroids is ineffective for preventing hypersensitivity reactions to contrast media. New guidelines recommend against these outdated protocols for iodinated contrast media and gadolinium-based contrast agents.
Area of Science:
- Radiology and Immunology
- Pharmacology
Background:
- Contrast media, including iodinated and gadolinium-based agents, are widely used but can cause hypersensitivity reactions.
- Current pretreatment protocols for these reactions are based on weak evidence and may cause harm.
Purpose of the Study:
- To evaluate the efficacy of current pretreatment strategies for contrast media hypersensitivity.
- To develop evidence-based recommendations for managing hypersensitivity reactions to contrast media.
Main Methods:
- A joint working group synthesized evidence on contrast media hypersensitivity.
- Reviewed epidemiology, risk factors, and pretreatment efficacy for iodinated and gadolinium-based contrast agents.
- Assessed allergy investigations and existing guidelines.
Main Results:
- Emerging evidence suggests longstanding pretreatment protocols are ineffective and potentially harmful.
- The efficacy of diphenhydramine and corticosteroids is not supported by strong evidence.
Conclusions:
- Pretreatment protocols for contrast media hypersensitivity require re-evaluation.
- Consensus-based recommendations were established to guide medical professionals and hospital policies.
Related Concept Videos
01:30Radiological Investigation I: X-ray and CT
206
Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
206
01:14Imaging Studies I: CT and MRI
189
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
189
01:13Radiological Investigation III: Pulmonary Angiogram and PET Scan
82
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
82
01:17Imaging Studies for Cardiovascular System I:Echocardiography
294
Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
294
01:20Imaging Studies for Cardiovascular System III: X-Ray
141
The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
141
01:25Imaging Studies II: Positron Emission Tomography and Scintigraphy
81
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Fundamental Principles of PET
81