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Gentamicin ointment effect on hard-to-heal wounds: a case series
Mary Cheney1, Mitchell Pei2, Kelsee Zajac2
1Jobst Vascular Institute, ProMedica Health Network, Wound Care Program, Toledo, Ohio, US.
Journal of Wound Care
|January 11, 2025
Summary
Topical gentamicin ointment effectively treated hard-to-heal wounds in a case series. This treatment reduced inflammation and promoted wound healing by targeting bacteria and biofilms.
Area of Science:
- Wound healing research
- Microbiology
- Dermatology
Background:
- Microbial presence in wounds causes inflammation, delaying healing of chronic wounds.
- Hard-to-heal wounds require effective antimicrobial strategies.
Purpose of the Study:
- To evaluate topical gentamicin ointment for treating hard-to-heal wounds.
- To assess gentamicin's efficacy in reducing inflammation and promoting wound closure.
Main Methods:
- Retrospective case series of 10 patients with hard-to-heal wounds.
- Treatment involved topical application of gentamicin ointment.
Main Results:
- All 10 patients showed positive response to topical gentamicin.
- Significant reduction in inflammation and wound size, with complete closure in some cases.
Conclusions:
- Topical gentamicin is a viable option for hard-to-heal wounds.
- Gentamicin may facilitate healing by eradicating bacterial biofilms and reducing inflammation.
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