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Skin Glue to Reduce Intravenous Catheter Failure in Children
Owen Chauhan1, Amy C Plint2, Nick Barrowman3
1Department of Emergency Medicine, IWK Health Centre, Dalhousie University, Halifax, NS, Canada.
Insights
Adding skin glue to peripheral intravenous catheters (IVs) did not reduce failure rates in children. This common pediatric emergency department procedure showed no significant difference in IV longevity when skin glue was used for securement.
Area of Science:
- Pediatric Emergency Medicine
- Medical Device Securement
- Clinical Trials
Background:
- Peripheral intravenous catheters (IVs) are essential but frequently fail in pediatric acute care.
- Catheter failure leads to patient discomfort and increased healthcare costs.
- Novel securement methods are explored to improve IV longevity.
Purpose of the Study:
- To evaluate the efficacy of adding cyanoacrylate skin glue to standard securement methods for peripheral IVs in children.
- To determine if skin glue reduces the rate of IV catheter failure in a pediatric emergency department setting.
Main Methods:
- A randomized controlled trial was conducted in a tertiary-care pediatric emergency department.
- Pediatric patients (<18 years) requiring IVs were randomized to standard securement or standard securement plus skin glue.
- The primary outcome was IV failure before completion of the intended treatment course, analyzed using intention-to-treat.
Main Results:
- 557 participants were enrolled; 527 were included in the intention-to-treat analysis.
- The IV failure rate was 31.3% in both the skin glue group (83/265) and the control group (82/262).
- No significant difference in the odds of IV failure (aOR 0.98; 95% CI, 0.67-1.42) or time to device failure (HR 0.99; 95% CI, 0.73-1.35) was observed between groups.
Conclusions:
- The addition of skin glue to standard securement techniques does not decrease the failure rate of peripheral IVs in pediatric emergency department patients.
- Current evidence does not support the routine use of skin glue for IV securement in this population.
- Further research may explore alternative securement strategies or specific pediatric subpopulations.
Study Objective:
The peripheral intravenous catheter (IV) is the most common and painful invasive medical device in acute care settings. Our objective was to determine whether adding skin glue to secure IVs reduced catheter failure rate in children.
Methods:
We conducted a randomized controlled trial in a tertiary-care pediatric emergency department (ED). ED patients younger than 18 years old with an IV who were anticipated to be admitted to hospital were eligible for enrollment. Children were randomized to receive standard IV securement with cloth-bordered transparent polyurethane dressing (control) or application of cyanoacrylate glue at the catheter insertion site in addition to standard securement (intervention). Participants were followed until device removal due to failure or physician order. The primary outcome was IV failure before the intended treatment course was complete. Patients who were randomized with primary outcome data were included in the intention-to-treat analysis.
Results:
Of the 557 participants enrolled between December 2020 and April 2023, 278 (50%) and 279 (50%) were allocated to the glue and control groups, respectively. A total of 527 participants were included in the intention-to-treat analysis. Intravenous failure rates in the glue and control groups were 83 of 265 (31.3%) and 82 of 262 (31.3%), respectively. The odds of intravenous catheter failure were not different between groups (adjusted odds ratio 0.98; 95% confidence interval, 0.67 to 1.42). Time to device failure was similar between groups (hazard ratio 0.99; 95% confidence interval, 0.73 to 1.35).
Conclusions:
This study found no benefit in using skin glue to secure IVs in the ED in children.
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