Related Experiment Video

Updated: Jun 3, 2025

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

19.7K

Rising cardiovascular mortality among obstructive sleep apnea patients: United States epidemiological trends

Dua Ali1, Shaheer Qureshi1, Hibah Siddiqui1

  • 1Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan.

Heart & Lung : the Journal of Critical Care
|January 11, 2025
PubMed

Insights

Obstructive sleep apnea (OSA) and cardiovascular disease (CVD) mortality rates have significantly increased, especially among men and Black individuals. Public health interventions are crucial to address disparities in high-risk groups.

Area of Science:

  • Public Health
  • Cardiology
  • Sleep Medicine

Background:

  • Obstructive sleep apnea (OSA) prevalence is rising globally, contributing to a significant healthcare burden.
  • OSA is a known risk factor for cardiovascular diseases (CVD), including heart failure, stroke, and ischemic heart disease.
  • Trends in CVD mortality among OSA patients are not well understood.

Purpose of the Study:

  • To analyze trends in mortality rates for obstructive sleep apnea (OSA) and cardiovascular disease (CVD) in the US.
  • To investigate variations in OSA-related CVD mortality based on demographics and geographic regions.

Main Methods:

  • Utilized CDC WONDER database for mortality data (adults ≥25 with OSA and CVD) from 1999-2019.
  • Calculated age-adjusted mortality rates (AAMRs) and annual percent change (APC) with 95% confidence intervals (CIs).
  • Stratified analyses by year, sex, race/ethnicity, age, urbanization, and Census regions.

Main Results:

  • Recorded 168,111 OSA-related CVD deaths between 1999 and 2019.
  • Observed significant increases in overall AAMRs, notably for hypertensive disease (APC: 13.2%).
  • Higher AAMRs in men vs. women, highest racial disparities in Black individuals, and highest rates in the Midwest and rural areas.

Conclusions:

  • OSA-related CVD mortality has substantially increased, highlighting significant disparities.
  • Marked variations in mortality exist across sex, race/ethnicity, and geographic regions.
  • Targeted public health interventions are essential to mitigate mortality in vulnerable populations.
Abstract

Keywords:
CDC WONDERCardiovascular DiseaseHealth DisparitiesMortalityObstructive Sleep ApneaTrends

More Related Videos

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach04:53

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach

Published on: October 18, 2024

689
Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders05:34

Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders

Published on: August 18, 2023

2.0K

Related Concept Videos

Sleep Apnea01:21

Sleep Apnea

Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
125
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
801
Chronic Obstructive Pulmonary Disease01:22

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
1.2K
Respiratory Volumes and Capacities I01:26

Respiratory Volumes and Capacities I

Assessing the respiratory rate and rhythm for a complete minute is crucial for evaluating the breathing pattern. Even a minor increase in the patient's average respiratory rate, by as little as three to five breaths per minute, is an early and vital indicator of respiratory distress. Patients with a respiratory rate exceeding twenty-four breaths per minute require close monitoring to determine the physiological alterations. This careful observation is essential for prompt recognition and...
814
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
2.7K
Physical Assessment of the Respiratory Tract II: Inspection01:27

Physical Assessment of the Respiratory Tract II: Inspection

Physical assessment of the respiratory tract through inspection is a crucial step in understanding the patient's respiratory health. It provides insights into the functioning of the respiratory system, the musculoskeletal structure, and even the patient's nutritional status. This comprehensive approach involves observing several vital aspects: chest configuration, breathing patterns, respiratory rates, skin color, and use of accessory muscles.
Chest Configuration
The chest configuration...
227