JoVE - Journal of Visualized Experiments
JoVE Visualize
Contact Us

Clear cell borderline ovarian tumor: A retrospective study and literature review

  • 0Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China; National Clinical Research Center for Obstetric & Gynecologic Diseases, China.
European Journal of Obstetrics, Gynecology, and Reproductive Biology +

|

January 11, 2025

|

January 11, 2025

View abstract on PubMed

Summary

This summary is machine-generated.

Clear cell borderline ovarian tumors have a favorable prognosis. Fertility-sparing surgery is a viable option for young patients, with unilateral salpingo-oophorectomy recommended after cystectomy.

Area Of Science

  • Gynecologic Oncology
  • Pathology
  • Reproductive Medicine

Background

  • Clear cell borderline ovarian tumors (CCBOTs) are rare, with limited understanding of their clinical behavior.
  • Clinicopathological features, management strategies, and prognostic outcomes for CCBOTs require further elucidation.

Purpose Of The Study

  • To characterize the clinicopathological features of CCBOTs.
  • To evaluate treatment options and patient prognosis for CCBOTs.

Main Methods

  • Retrospective analysis of nine patients with pathologically confirmed CCBOTs (2006-2023).
  • Review of published English literature on CCBOTs treated with fertility-sparing surgery.

Main Results

  • Median age at diagnosis was 52 years; median tumor size was 6.5 cm.
  • Seven patients had unilateral, two had bilateral tumors; seven underwent radical surgery, two fertility-sparing surgery.
  • One recurrence occurred during a median follow-up of 54 months, successfully treated with secondary surgery.

Conclusions

  • CCBOTs demonstrate a favorable prognosis.
  • Fertility-sparing surgery is a suitable option for young patients desiring future pregnancies.
  • Unilateral salpingo-oophorectomy is advised post-ovarian cystectomy for CCBOTs.

Keywords: