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Related Concept Videos

Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

53
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
53
Biological Causes of Schizophrenia01:29

Biological Causes of Schizophrenia

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Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
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Personality Disorders: Paranoid and Schizoid01:22

Personality Disorders: Paranoid and Schizoid

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Personality disorders represent enduring cognition, affect, and behavior patterns that significantly deviate from societal norms. These maladaptive traits often lead to difficulties in various domains, including interpersonal relationships, occupational settings, and overall psychological well-being. Paranoid personality disorder and schizoid personality disorder are two distinct conditions marked by odd or eccentric behavior.
Paranoid Personality Disorder
Paranoid personality disorder is...
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Negative and Cognitive Symptoms of Schizophrenia01:30

Negative and Cognitive Symptoms of Schizophrenia

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Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
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Schizophrenia01:17

Schizophrenia

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Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those...
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Positive Symptoms of Schizophrenia: Hallucinations and Delusions01:30

Positive Symptoms of Schizophrenia: Hallucinations and Delusions

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Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
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Related Experiment Video

Updated: Jun 3, 2025

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia
13:08

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Social functioning and frontal alpha asymmetry in schizophrenia.

Emily A Farina1, Michal Assaf2, Silvia Corbera3

  • 1Yale University School of Medicine and the Connecticut Mental Health Center, New Haven, CT, USA; Department of Psychological Sciences, University of Connecticut, 406 Babbidge Road, Unit 1020, Storrs, CT, USA.

Journal of Psychiatric Research
|January 12, 2025
PubMed
Summary

Frontal alpha asymmetry (FAA) measured by EEG does not appear to be a reliable neurophysiological marker for social functioning deficits in schizophrenia. However, FAA did correlate with social functioning in healthy individuals, and showed similarities between schizophrenia and autism spectrum disorder groups.

Keywords:
Autism spectrum disorderElectroencephalogramFrontal alpha asymmetrySchizophreniaSocial functioning

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Clinical Psychology

Background:

  • Schizophrenia (SZ) is characterized by impaired social functioning.
  • Frontal alpha asymmetry (FAA), derived from EEG, may indicate motivational and emotional tendencies.
  • FAA has been hypothesized as a potential neurophysiological marker for social deficits in SZ.

Purpose of the Study:

  • To investigate the relationship between FAA and social functioning in individuals with schizophrenia.
  • To explore if observed FAA patterns in schizophrenia are unique or also present in autism spectrum disorder (ASD).

Main Methods:

  • Utilized resting-state EEG, clinical interviews, and self-report measures.
  • Employed analysis of variance and regression models for data evaluation.
  • Compared data from 33 participants with SZ, 38 healthy controls, and 30 individuals with ASD.

Main Results:

  • While SZ participants showed altered FAA compared to controls, it did not correlate with their social functioning.
  • FAA was significantly related to social functioning in the non-psychiatric control group.
  • Schizophrenia and ASD groups exhibited similar patterns of FAA and social functioning, suggesting shared characteristics.

Conclusions:

  • FAA is unlikely a neurophysiological marker for reduced social functioning in schizophrenia.
  • Further research is warranted to explore FAA's role in other shared clinical features between schizophrenia and ASD.