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Updated: Jul 6, 2026

Assessment of Endothelial Cell Migration After Exposure to Toxic Chemicals
Published on: July 10, 2015
Safety assessment of natural materials for food contact in high temperature applications: Migration studies with
Sofia Nieves1, Cristina Nerín1, Esther Asensio1
1Department of Analytical Chemistry, Aragon Institute of Engineering Research I3A, EINA-University of Zaragoza, Torres Quevedo Building, María de Luna 3, 50018 Zaragoza, Spain.
Abstract:
The concern of conventional plastics for food contact has opened the use of natural vegetal materials which can be used even at high temperature. However, their safety in use has to be carefully evaluated. This study shows the migration tests of volatile compounds to Tenax® at 175 °C for 1 h. Hexadecanoic, octadecanoic and tetracosanoic acid were detected and quantified, presenting values well below the specific migration limits (SML) according to Regulation (EU) No 10/2011. Aldehydes were detected and semi-quantified and were generally below the migration limits established for compounds without SML. Compounds related to the manufacturing process of different types of food contact materials (FCM) were identified. The use of this type of dishes made from natural materials does not present a risk to the consumer due to the migration of volatile compounds when used at high temperature, in accordance with the conditions of use set by the manufacturer.
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