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Digital screening tool for the assessment of cognitive impairment in unsupervised setting-digiDEM-SCREEN: study
Michael Zeiler1, Nikolas Dietzel2, Klaus Kammerer3
1Institute for Medical Informatics, Biometrics and Epidemiology, Medical Informatics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
BMJ Open
|January 12, 2025
Summary
This study validates the digiDEM-SCREEN app for early dementia detection. The digital tool aims to improve diagnosis rates for cognitive impairments, making screening more accessible.
Area of Science:
- Neurology
- Digital Health
- Cognitive Science
Background:
- Dementia affects 55 million globally, with 60-75% undiagnosed.
- Early diagnosis is crucial for effective management.
- Digital screening tools offer accessible, convenient cognitive assessment.
Purpose of the Study:
- To validate the digiDEM-SCREEN app for cognitive screening in German.
- To assess the app's utility in identifying mild cognitive impairment and early dementia.
- To enhance dementia diagnosis rates through accessible digital tools.
Main Methods:
- Multicentre study in Bavaria involving 135 participants.
- Inclusion of individuals with mild cognitive impairment, early dementia, and healthy controls.
- Comparison of digiDEM-SCREEN with established neuropsychiatric tests (CERAD, MoCA).
Main Results:
- Sensitivity, specificity, and cut-off values will be determined using ROC curves.
- Correlation analysis between digiDEM-SCREEN and existing cognitive tests.
- Validation of digiDEM-SCREEN as a reliable digital screening tool.
Conclusions:
- The digiDEM-SCREEN app provides feedback on cognitive status.
- It encourages users to seek professional diagnosis for potential impairments.
- Results will be published in peer-reviewed journals and the app will be freely available.

