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Updated: Jun 3, 2025

Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice
Published on: March 15, 2019
Does mental exertion during incremental exercise change substrate oxidation and cardiorespiratory outcomes in
Samira Pourmirzaei Kouhbanani1, Seyed Kamaledin Setarehdan2, Rana Fayazmilani1
1Department of Biological Sciences in Sport, Faculty of Sport Sciences and Health, Shahid Beheshti University, Tehran, Iran.
Abstract:
Given the growing concern over the impact of brain health in individuals with overweight, understanding how mental exertion (ME) during exercise affects substrate oxidation and cardiorespiratory outcomes is crucial. This study examines how ME impacts these outcomes during an incremental exercise test in adults with overweight. Seventeen adults who were overweight completed an incremental exercise test on a cycle ergometer two times, with and without the Stroop task. Energy expenditure (EE), carbohydrate and fat oxidation, maximum heart rate (HRmax), maximal oxygen uptake (VO2max), maximum fat oxidation (MFO), and the intensity of exercise that elicited MFO (Fatmax) are measured by indirect calorimetry. ME did not change the EE, carbohydrate, and fat oxidation at any stages of the incremental test. However, ME resulted in significantly lower HRmax, VO2max, and MFO (p < 0.01) and increased NASA-TLX scores but showed no change in Fatmax. These results show ME decreases the value of HRmax, VO2max, and MFO during the incremental exercise test. Due to the increased mental workload demonstrated by the NASA-TLX test, adults with overweight are unable to complete the test to the same extent as they did in the test without ME according to maximal levels in this study.
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