Related Experiment Video
Updated: May 3, 2026
A Hydrogel Construct and Fibrin-based Glue Approach to Deliver Therapeutics in a Murine Myocardial Infarction Model.
Published on: June 14, 2015
Cardiovascular patches applied in congenital cardiac surgery: Current materials and prospects
Mingze Sun1, Vincent Reed LaSala1, Caroline Giuglaris1,2
1Department of Surgery Columbia University New York New York USA.
Insights
This review examines cardiovascular patches (CVPs) used to repair congenital heart defects (CHDs) in children. It assesses patch history, types, applications, and performance to aid clinical and research decisions.
Area of Science:
- Biomedical Engineering
- Pediatric Cardiology
- Surgical Innovation
Background:
- Congenital Heart Defects (CHDs) are the most common birth anomalies, impacting 4-75 per 1000 live births.
- Cardiovascular patches (CVPs) are essential surgical tools for reconstructing heart structures in pediatric patients with CHDs.
Purpose of the Study:
- To provide a comprehensive review of cardiovascular patches (CVPs).
- To evaluate the history, available options, clinical applications, and features of CVPs.
- To assess the performance and outcomes of various CVP materials for clinical and research guidance.
Main Methods:
- Literature review of historical and current cardiovascular patch technologies.
- Analysis of clinical applications and outcomes associated with different CVP materials.
- Synthesis of data to compare patch performance for surgical reconstruction in CHDs.
Main Results:
- Overview of the evolution of cardiovascular patch materials and designs.
- Comparison of clinical performance data for various CVP options.
- Identification of key features influencing patch efficacy in pediatric CHD repair.
Conclusions:
- Cardiovascular patches are critical in managing pediatric congenital heart defects.
- Understanding patch history, materials, and performance is vital for optimal surgical outcomes.
- This review serves as a reference for clinicians and researchers in CVP selection and development.
Abstract:
Congenital Heart Defects (CHDs) are the most common congenital anomalies, affecting between 4 and 75 per 1000 live births. Cardiovascular patches (CVPs) are frequently used as part of the surgical armamentarium to reconstruct cardiovascular structures to correct CHDs in pediatric patients. This review aims to evaluate the history of cardiovascular patches, currently available options, clinical applications, and important features of these patches. Performance and outcomes of different patch materials are assessed to provide reference points for clinicians. The target audience includes clinicians seeking data on clinical performance as they make choices between different patch products, as well as scientists and engineers working to develop patches or synthesize new patch materials.
