Related Experiment Video

Updated: Jun 3, 2025

A Reverse Genetic Approach to Test Functional Redundancy During Embryogenesis
06:59

A Reverse Genetic Approach to Test Functional Redundancy During Embryogenesis

Published on: August 11, 2010

12.0K

Specific, or not specific, that is the question: Is Cre recombinase deleting your favorite gene only in

Onne A H O Ronda1, H Llewelyn Roderick1

  • 1Laboratory of Experimental Cardiology, Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium.

Journal of Molecular and Cellular Cardiology Plus
|January 13, 2025
PubMed
Abstract

No abstract available in PubMed .

More Related Videos

Improved Generation of Induced Cardiomyocytes Using a Polycistronic Construct Expressing Optimal Ratio of Gata4, Mef2c and Tbx5
10:05

Improved Generation of Induced Cardiomyocytes Using a Polycistronic Construct Expressing Optimal Ratio of Gata4, Mef2c and Tbx5

Published on: November 13, 2015

8.6K
Visualization of Cell Cycle Variations and Determination of Nucleation in Postnatal Cardiomyocytes
09:41

Visualization of Cell Cycle Variations and Determination of Nucleation in Postnatal Cardiomyocytes

Published on: February 24, 2017

8.7K

Related Experiment Videos

Last Updated: Jun 3, 2025

A Reverse Genetic Approach to Test Functional Redundancy During Embryogenesis
06:59

A Reverse Genetic Approach to Test Functional Redundancy During Embryogenesis

Published on: August 11, 2010

12.0K
Improved Generation of Induced Cardiomyocytes Using a Polycistronic Construct Expressing Optimal Ratio of Gata4, Mef2c and Tbx5
10:05

Improved Generation of Induced Cardiomyocytes Using a Polycistronic Construct Expressing Optimal Ratio of Gata4, Mef2c and Tbx5

Published on: November 13, 2015

8.6K
Visualization of Cell Cycle Variations and Determination of Nucleation in Postnatal Cardiomyocytes
09:41

Visualization of Cell Cycle Variations and Determination of Nucleation in Postnatal Cardiomyocytes

Published on: February 24, 2017

8.7K

Related Concept Videos

Conservative Site-specific Recombination and Phase Variation02:53

Conservative Site-specific Recombination and Phase Variation

5.9K
Because the DNA segments are cut and reorganized in a direction-specific manner, site-specific recombination has emerged as an efficient genetic engineering technique. Flippase and Cyclization recombinases or Flp and Cre, respectively, are two members of the tyrosine recombinase family derived from bacteriophages, that are used to mediate site-specific DNA insertions, deletions, and targeted expression of proteins in mammalian cell lines.
The recognition sites for Cre recombinase called LoxP...
5.9K

Articles linked to this work by shared authors, journal, and citation graph.

Resolution and automated analysis of single-cell Ca2+ waves within living myocardial tissue slices.

The Journal of physiology·2026

Single-Nucleus RNA-Seq of Human and Rat Cardiomyocytes Identifies Shared and Distinct Regulators and Features of Aging and Disease.

Aging and disease·2026

ERBB4 activation as a new therapy for atrial remodeling and fibrillation.

Heart rhythm·2026

Sodium-myo-inositol cotransporter-1, SMIT1, promotes cardiac hypertrophy and fibrosis induced by pressure overload in mice.

Cardiovascular research·2026

Patient-Derived 3D Bioprinted Cardiac Organoid Constructs Reveal Key Pathological Features of Duchenne Muscular Dystrophy.

Advanced healthcare materials·2026

Location and aetiology are determinants of fibroblast activation and heterogeneity in the failing human heart.

Genome medicine·2025

CardioPharmaGENET (CA24165): A COST action network for advancing cardiovascular pharmacogenomics and precision medicine.

Journal of molecular and cellular cardiology plus·2026

Systemic inflammation increases mast cell numbers in coronary arteries in patients who died from myocardial infarction.

Journal of molecular and cellular cardiology plus·2026

Systemic administration of the PRMT5 inhibitor GSK3326595 does not induce overt cardiotoxicity in the murine heart.

Journal of molecular and cellular cardiology plus·2026

Evidence for a role of adverse sarcomere signaling in atrial fibrillation induction.

Journal of molecular and cellular cardiology plus·2026

Heterogeneous nuclear ribonucleoprotein A1 as a candidate associated with pulmonary vascular remodeling in pulmonary arterial hypertension.

Journal of molecular and cellular cardiology plus·2026

Netrin-1 suppresses CCL2-driven macrophage migration: implications for modulating vascular inflammation and aortic sinus enlargement in hyperlipidaemic mice.

Journal of molecular and cellular cardiology plus·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us