Related Experiment Video
Updated: Jul 15, 2026

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
Published on: December 3, 2017
A Rare Case of Staphylococcus Caprae Periprosthetic Hip Infection with Unusual Clinical Presentation
Daniele Grassa1,2, Francesco Cavola1,2, Alessandro Giuliani1,2
1Adult Reconstruction and Joint Replacement Service, Division of Sports Traumatology and Joint Surgery, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Largo Agostino Gemelli 8, Roma, RM 00168, Italy.
Introduction:
Total hip arthroplasty (THA) surgeries are rapidly increasing due to an aging population, leading to an increase in degenerative hip osteoarthritis. However, 1% of these patients go through prosthetic joint infection (PJI), which gives rise to implant failure with prolonged periods of patient incapacitation and higher mortality risk.
Case Report:
In this article, we report an unusual case of a 62-year-old male who developed a PJI 7 months after a THA. The patient complained of groin, buttock pain, and swelling. He underwent MRI examination, which revealed the presence of a voluminous three-lobed formation with liquid content located around the prosthesis. After several attempts where microbiological samples reported negative results, a microbiological sample came out positive for Staphylococcus Caprae at the time of femoral component sonication. S. caprae is a Gram-positive bacillus belonging to the Staphylococcus spp. It is most commonly found as a commensal in goats and sheep, but it is a rare pathogen in human infections. The patient underwent two-stage revision surgery, resulting in the total resolution of the infection.
Conclusion:
Staphylococcus Caprae still remains an unusual cause of infection. We report the 11th hip PJI due to S. caprae successfully treated with a two-stage exchange protocol.
Related Concept Videos
Endocarditis I: Introduction
Acute Pyelonephritis II: Diagnostic Studies and Management
Staphylococcal Skin Infections
Atypical Pneumonia
Clinical Significance of Antibiotic Resistance
Brain Abscess l: Introduction

