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Updated: Jun 15, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Repairing the mitral valve without touching the mitral valve-a novel technique
Daniel Sitaranjan1, Ujjawal Kumar1,2, Fadi Al-Zubaidi1
1Department of Cardiac Surgery, Royal Papworth Hospital, Papworth Road, Cambridge Biomedical Campus, Cambridge, Cambridgeshire CB2 0AY, United Kingdom.
Insights
Severe left ventricular aneurysm and mitral regurgitation were successfully treated with aneurysmectomy and geometric restoration, improving cardiac function. This approach avoided direct mitral valve intervention, showcasing its efficacy in complex cardiac cases.
Area of Science:
- Cardiology
- Cardiac Surgery
- Cardiovascular Imaging
Background:
- Severe ischemic cardiomyopathy and mitral regurgitation pose significant clinical challenges.
- Left ventricular aneurysms can lead to heart failure and thromboembolic events.
- Accurate diagnosis relies on advanced imaging like echocardiography and MRI.
Observation:
- A 44-year-old male presented with a large left ventricular aneurysm (9.3 x 9.5 cm) and severe mitral regurgitation post-myocardial infarction.
- Imaging revealed a dilated left ventricle, thrombus within the aneurysm, and significant leaflet tethering causing mitral regurgitation.
- Pre-operative left ventricular ejection fraction was markedly reduced at 25%.
Findings:
- The patient underwent successful aneurysmectomy with patch repair and papillary muscle approximation.
- Postoperatively, temporary veno-arterial extracorporeal membrane oxygenation (ECMO) support was required for 6 days.
- The patient was discharged with improved left ventricular ejection fraction (45%) and only trace mitral regurgitation.
Implications:
- Geometric restoration of the left ventricle can effectively address severe mitral regurgitation secondary to aneurysm.
- This surgical strategy offers a viable alternative to conventional mitral valve repair or replacement in select cases.
- Successful management highlights the importance of addressing ventricular remodeling in ischemic heart disease.
Abstract:
A 44-year-old gentleman presented with severe ischemic cardiomyopathy and mitral regurgitation post-inferior myocardial infarction. Echocardiography and magnetic resonance imaging revealed a dilated left ventricle with a large left ventricular aneurysm (9.3 × 9.5 cm) and associated thrombus. Severe mitral regurgitation due to leaflet tethering and a left ventricular ejection fraction (LVEF) of 25% were also seen. The patient underwent successful aneurysmectomy with patch repair and papillary muscle approximation. Following initial weaning from cardiopulmonary bypass, 6 days of postoperative temporary veno-arterial extracorporeal membrane oxygenation support were required. The patient was subsequently discharged on postoperative day sixteen with improved cardiac function (LVEF of 45%) and trace residual mitral regurgitation, highlighting the efficacy of geometric restoration in addressing such mitral regurgitation, avoiding conventional intervention on the mitral valve itself.
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