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Nicolau syndrome: A case of ischemic necrosis after subcutaneous immunotherapy

Joyce Kim1, Tim Kaddis2, Spencer Boyle2

  • 1Department of Medicine, University of California Los Angeles, Los Angeles, Calif.

The Journal of Allergy and Clinical Immunology. Global
|January 13, 2025
PubMed

A rare injection site reaction known as Nicolau syndrome can occur in patients receiving subcutaneous immunotherapy. This syndrome has been reported only a handful of times in the literature related to subcutaneous immunotherapy.

Keywords:
Nicolau syndromeSubcutaneous immunotherapyembolia cutis medicamentosaischemic necrosis

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