Related Experiment Video
Updated: May 5, 2026

09:53
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
3.5K
Idiopathic Intracranial Hypertension: Pre- and Post-treatment Radiologic Analyses
José Diogo Martins1,2, Pedro Mesquita3, Joana Alves Costa4
1Internal Medicine, Unidade Local de Saúde do Alto Minho, Viana do Castelo, PRT.
Cureus
|January 13, 2025
Summary
Idiopathic intracranial hypertension (IIH) can cause vision loss and headaches. Prompt diagnosis and acetazolamide treatment effectively resolved symptoms in a young female patient.
Area of Science:
- Neurology
- Ophthalmology
Background:
- Idiopathic intracranial hypertension (IIH) is a neurological disorder characterized by increased intracranial pressure without an identifiable cause.
- It commonly affects women of childbearing age and can lead to significant visual impairment.
Observation:
- A 19-year-old female presented with symptoms of pressure headaches and progressive vision loss.
- Diagnostic evaluations, including CT, MRI, and lumbar puncture, were performed.
Findings:
- Imaging and lumbar puncture results were consistent with a diagnosis of idiopathic intracranial hypertension (IIH).
- Treatment with acetazolamide effectively reduced intracranial pressure and alleviated the patient's symptoms.
Implications:
- This case highlights the importance of timely diagnosis and medical management of IIH.
- Acetazolamide is an effective therapeutic option for managing IIH and preventing vision loss.
Related Concept Videos
Increased Intracranial Pressure l: Introduction
27
Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component...
27
Increased Intracranial Pressure ll: Pathophysiology
20
Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins...
20

