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Updated: Jun 2, 2025

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Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
Published on: February 10, 2023
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Screening for Deep Vein Thrombosis Using D-dimer Levels Based on Surgical Patients' Characteristics
Fumimasa Kitamura1, Yuta Shiraishi1, Kazuya Sakata1
1Surgical Gastroenterology, Amakusa Regional Medical Center, Amakusa, JPN.
Cureus
|January 13, 2025
Summary
Low body mass index and elevated D-dimer levels predict deep vein thrombosis (DVT) risk in surgical patients. D-dimer screening can help reduce unnecessary preoperative tests, optimizing surgical care.
Area of Science:
- Medical Science
- Surgical Care
- Diagnostic Imaging
Background:
- Healthcare systems face challenges with surgeon shortages and reduced medical staff.
- Minimizing unnecessary diagnostic tests is crucial to alleviate staff burden in regional medical care.
Purpose of the Study:
- To identify predictors of deep vein thrombosis (DVT) in surgical patients.
- To evaluate the feasibility of using D-dimer levels for DVT screening preoperatively.
Main Methods:
- Retrospective analysis of 310 surgical cases with preoperative lower extremity ultrasonography.
- Comparison of 46 patients with DVT (thrombi) and 264 patients without DVT.
Main Results:
- Low body mass index (<18.5 kg/m²) and high D-dimer levels (>2 μg/mL) significantly increased DVT risk.
- Oral antiplatelet drugs and anticoagulants were associated with a lower risk of DVT.
- D-dimer levels showed an area under the curve of 0.779 for DVT prediction, with a threshold of 1.4 μg/mL achieving 100% sensitivity.
Conclusions:
- D-dimer levels show potential effectiveness in predicting DVT risk in surgical patients.
- Integrating D-dimer levels with patient background information may help reduce excessive preoperative testing.
- Optimizing diagnostic strategies can improve efficiency in surgical patient management.
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