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Updated: May 11, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Propofol-Induced Fasciculations in a Patient With Obstructive Sleep Apnea: A Case Report
Jaden Y Fang1, Tomohiro Yamamoto2, Satoshi Yamamoto1
1Anesthesiology, University of Texas Medical Branch, Galveston, USA.
Abstract:
We report a case of a 39-year-old male patient who developed propofol-induced fasciculations during the induction of general anesthesia. The patient had a history of moderate obstructive sleep apnea and was intolerant to continuous positive airway pressure therapy. He subsequently underwent the insertion of a hypoglossal nerve stimulator as a viable surgical intervention. The patient had a drug-induced sleep endoscopy that showed a 100% obstruction at the velum and the oropharynx, mainly in the anteroposterior and lateral directions. The patient experienced a smooth induction and emergence from general anesthesia, except for a brief episode of myoclonus-like movement in the bilateral upper extremities after propofol administration. The patient recovered well and reported an improvement in his sleep quality and daytime symptoms.
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