A Rare Case of Bladder Melanosis: A Case Report and Review of the Literature
Related Experiment Video
Updated: Jun 2, 2025

Mouse Bladder Wall Injection
Published on: July 12, 2011
Ben Walters1, Srinath Ileperuma1, Andleeb Abrari2
1Urology, Rotherham District General Hospital, Rotherham, GBR.
Abstract:
Bladder melanosis is a rare and poorly understood condition involving melanin pigmentation within the urothelial mucosa. Cases often present with haematuria, urinary obstructive symptoms, or cystitis. While generally considered benign, its potential association with malignancy warrants regular monitoring, as cases have previously been reported of an association with urothelial carcinoma and melanoma, although it is unclear whether there is a causal relationship. Here, we present the case of a fit and well 51-year-old male who was diagnosed incidentally with bladder melanosis following cystoscopy and perform a thorough literature review of all known cases.

